In addition, some polyphenols can enhance the anti-tumour effect while antagonizing ototoxicity.Although polyphenols show good application prospects in the prevention and treatment of cisplatin ototoxicity, there are still some problems that need to be solved, such as the low bioavailability of polyphenols, the mechanism of action has not yet been fully elucidated, the optimal dosing regimen has not yet been determined, whether there is any superimposed effect of combining the various types of polyphenols, and whether the oral polyphenols can exert an otoprotective effect through the regulation of the intestinal flora through the intestinal-auricular axis.This study provides new insights into polyphenols as potential drug candidates for CIO by summarising the cytotoxic mechanisms of cisplatin and the mechanism of action of polyphenols targeting these mechanisms in order to retard the progression of CIO
Step 4: Moisturizer Choose a lightweight moisturizer that wont interfere with SPF application but provides adequate barrier support, we suggest Omega Water Cream
IV therapy is suitable for most healthy adults looking to improve hydration, boost energy, or support overall wellness
The body makes this itself, but you can also take it as a supplement
L-Glutathione (USP) 500mg
Experimental data show that BPC-157 promotes VEGFR2 signaling and upregulates endothelial nitric oxide synthase (eNOS) through the SrcCaveolin-1 pathway, resulting in improved vasomotor tone and blood flow restoration
