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The encapsulation of peptides helps protect them from degradation in the digestive tract, ensuring better absorption and bioavailability

56 These trials demonstrate that although orforglipron is safe and efficacious more longitudinal research is warranted to provide deeper insights into their efficacy, safety and tolerability before their potential incorporation in the pharmacological arsenal against T2DM or obesity

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Two other mitochondrial-derived peptides (MDPs) have also been discovered so far, humanin and SHLP1-6, but their possible involvement in human performance enhancement is unknown

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