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Common signs may include: Persistent fatigue or low energy Difficulty concentrating Mood changes Weakness or dizziness Tingling in the hands or feet Individuals who follow restrictive diets or have certain digestive conditions may be more likely to experience low vitamin B12 levels

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The purpose of this treatment is to eliminate matrix constituents that could interfere with the detection process or damage analytical equipment, and to enrich the analyte in the sample so that it is readily available for detection [3], [2]

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