Analytical quality control of cognitive peptides Short cognitive peptides (6-8 residues) impose specific analytical constraints: MS identity : ESI-LRMS is sufficient for these short sequences
Mitochondrial function, GSH and iron in neurodegeneration and Lewy body diseases
Curr Pharm Des 20:11211125 Sellin LC, Laakso PS (1987) Antagonism of ethanol-induced depressant effects by 4-aminopyridine in the central nervous system of the rat
Additionally, the Alzheimers Association released its first clinical practice guideline on the use of blood-based biomarkers in 2025, signaling that these tools are transitioning from research settings into real diagnostic pathways, grounding novel biomarkers into meaningful clinical action. Research into the treatment of Alzheimers disease continued to advance as well
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Iron regularly appears as a ferrous (Fe(II)) or as a ferric ion (Fe(III)) and is able to accept an electron from neighboring molecules which leads to the generation of ROS and causes damage to cellular components