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Probiotics Antimicrob Proteins 11:509518

10.1007/s00423-018-1724-8 56 KltingN.BlherM

This path avoids stomach acid and firstpass liver metabolism, often leading to much higher and faster bioavailability than standard capsules

doi: 10.1101/cshperspect.a029009 98 HolleyJEGvericDNewcombeJCuznerMLGutowskiNJ

While CB-839 inhibited the proliferation of patient-derived glioma cell lines, it did not affect cell viability (103).In NSCLC, KEAP1 mutant NSCLC cell lines exhibit a dependence on Gln, and the GLS inhibitor CB-839 can inhibit Gln metabolism to exert anti-tumor effects (104)

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