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When weightlifting, try doing some high-intensity interval (HIIT) training or doing cardiovascular exercise for any extended period

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This makes it useful in trials that track short-term changes in body composition or performance

It works by changing how your body processes and responds to food at a fundamental hormonal level

The Primary Glucose-Lowering Effect of Metformin Resides in the Gut, Not the Circulation: Results From Short-Term Pharmacokinetic and 12-Week Dose-Ranging Studies

For a broader look at hydration and appetite changes during treatment, The GLP-1 Diet: What to Eat for Real Results in 2026 is a helpful place to start