Although we have focused on the mitochondria as we believe that this core respiratory deficiency is the most important example of a copper-dependent system as it governs metabolism (Ruiz et al., 2021), it is necessary to point out the key role of other copper-dependent systems that would be compromised in the brain-wide copper deficiency we see in AD
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Zinc decreases C-reactive protein, lipid peroxidation, and inflammatory cytokines in elderly subjects: a potential implication of zinc as an atheroprotective agent
Another patient with chronic inflammation noticed lower inflammation markers and better health after three months
GSH is synthesized from cysteine, glutamate, and glycine by the ATP-dependent enzyme -glutamyl-cysteine (-GC) ligase (GCL) synthetase, which is composed of the -GC ligase catalytic subunit (GCLC), the -GC modifier subunit (GCLM), and GSH synthetase (GSS) 24
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