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CPT1 was identified as part of a large protein complex of the mitochondrial outer membrane, protruding toward the cytosol, which includes long-chain acyl-CoA synthetase (ACSL) and the voltage-dependent anion channel (VDAC) also known as porin (Figure 1)

This is the same drug used to treat type 2 diabetes under the brand name Ozempic, but at a higher dose

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GLP-1s therapies can level the playing field against biology

The clinical relevance of these observations is currently unknown, since only a few randomized clinical studies with renal endpoints have been conducted so far

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