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10.2139/ssrn.5775637 22 GrahamD

Rheumatoid synovial fibroblasts differentiate into distinct subsets in the presence of cytokines and cartilage

Unlike the traditional one drug-one target-one disease paradigm, network-based drug discovery reveals disease mechanisms from a holistic perspective, fully considering the complexity of biological systems [10]

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Research suggests Spadin might indirectly influence BDNF regulation, possibly through serotonin signaling and TREK-1 modulation

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