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Sources: Journal of Nutrition

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Liver injury in NAFLD is caused by two mechanisms in general: (1) by peripheral resistance to insulin, and (2) by intrahepatic oxidative stress, whether with an increase of reactive oxygen species and reactive nitrogen species (ROS and RNS) and/or as a result of the decrease in antioxidant tissue levels

Some of these molecules have also entered clinical trials and we will possibly welcome in the future the approval of a GST inhibitor or pro-drug for the treatment of patients

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Dietary quercetin abrogates hepatorenal oxidative damage associated with dichloromethane exposure in rats