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Second, competitive depletion of arginine suppresses T cell immunoreactivity, e.g., glioblastoma depletes arginine from the microenvironment through upregulation of arginase (ARG1), leading to inactivation of CD8 + T cell function and promoting immune escape(Mart and Reith 2021)

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AOD9604 is a synthetic peptide derived from a fragment of human growth hormone (HGH), specifically amino acids 177191 of the HGH molecule

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