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Avoid areas around scars, moles, or skin blemishes

This effect was also present for IL-4 levels and IL-10, in which elevated levels of IL-4 (all p 0.014

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The practical safety considerations are all related to the side effects of the medication rather than the training itself: Nausea: Most common during dose titration

The side effects were most commonly gastrointestinal disturbances such as nausea and vomiting and occurred in a similar frequency to those reported with dual receptor co-agonists [61]