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For cDNA-transfected cells, NanoGlo Live Cell Reagent with furimazine (1:40 dilution in HBSS) was added and relative luciferase units (RLU) recorded at 460 nm using a Flexstation 3 microplate reader

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Subgroup analyses showed, however, that apixaban was associated with greater mortality in certain subgroups, including patients with diabetes and those using digoxin (Lanoxin)

The findings were published recently in the Canadian Journal of Physiology and Pharmacology