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We found that PPARa over-expression significantly up-regulated FSP1 expression in neuron after TSCI, thus promoted the expression of CoQ10 and content of NADH, while icFSP1 inhibited this phenomenon, suggesting that FSP1 is a key effector of PPARa mediated lipid peroxidation related neuronal ferroptosis protection

10.1007/s00262-022-03334-x 87 KawamotoY.MorizaneC.KomatsuY.KondoS.UenoM.KobayashiS.et al (2024)

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