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In their separate trials, the Wegovy pill averaged about 13.6% over 64 weeks and Foundayo about 11.2% over 72 weeks at the top dose
Many people begin GLP-1 drug therapy expecting rapid, dramatic changesbut what they dont realize is that outcomes can vary widely based on factors like metabolism, diet, activity levels, and even how the body individually responds to these medications
If using tirzepatide, women should discuss contraception, as backup methods are recommended during initiation and for 4 weeks after dose increases
Management strategies for GLP-1 users: Start with lower doses when possible Avoid high-sulfur protein-heavy meals Eat smaller, more frequent meals Maintain excellent hydration Consider temporary digestive aids Discuss dose adjustments with your healthcare provider If you are experiencing sulfur burps specifically on Mounjaro, see our dedicated guide: Does Mounjaro Cause Sulfur Burps
Discontinue use and consult your doctor if any adverse reactions occur
Notably, semaglutide does not substantially increase energy expenditure
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