Conclusion This study clarifies the key role of dopamine and D2 receptors in the mOFC in chronic migraine: in CM model mice, dopamine release in the mOFC is increased, which activates dopamine D2 receptor and inhibits excitatory DRD2+ neurons dominated by Camk2a, thereby improving pain hypersensitivity and anxiety-like behavior
C th bn to ra mt s cht chng oxy ha, nhng nhng cht khc n t cc ngun bn ngoi nh ch n ung ca bn hoc cc cht b sung nh Glutathione
Lancet (London, England) 403(10437):16351648 Shah SJ, Sharma K, Borlaug BA, Butler J, Davies M, Kitzman DW, Petrie MC, Verma S, Patel S, Chinnakondepalli KM et al (2024) Semaglutide and diuretic use in obesity-related heart failure with preserved ejection fraction: a pooled analysis of the STEP-HFpEF and STEP-HFpEF-DM trials
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These differences may have resulted in a relative reduction in effect sizes when pooling cross-sectional estimates obtained in the main analyses and those from 6-year follow-up analyses
Moscarello, J
