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doi: 10.3389/fphar.2022.838133 Received 17 December 2021 Accepted 03 February 2022 Published 25 February 2022 Volume 13 - 2022 Edited by Domenico Ribatti, University of Bari Aldo Moro, Italy Reviewed by Benedetta Bussolati, University of Turin, Italy Lasse Dahl Ejby Jensen, Linkping University, Sweden Antonio Giovanni Solimando, University of Bari Aldo Moro, Italy Updates Copyright 2022 Ayoub, Jaradat, Al-Shami and Alkhalifa

GIPR agonism supports glucose-dependent insulin release and lipid metabolism, while GCGR activation is linked to increased energy expenditure, hepatic lipolysis, and thermogenesis processes that together distinguish it from earlier incretin-based research compounds such as semaglutide and tirzepatide

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BPC-157 Short for Body Protection Compound 157

Hormonal birth control: Other GLP-1 medications have been shown to potentially decrease the efficacy of oral birth control pills