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Additionally, the thiol side chain of cysteines serve as potent nucleophiles and react with oxidants and electrophilic species that would otherwise cause damage to the cell

[PubMed: 19489786] 373

10.1007/978-3-030-68748-9_11 Adv Exp Med Biol

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Also, remember, if using a PPI long term, it is important to wean slowly off those medicines, as stopping abruptly can cause worsening reflux symptoms for the next several days, as the stomach acid may increase again quickly