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In this trial, 195 adult patients exposed to JARDIANCE had an eGFR between 60 and 90 mL/min/1.73 m2, 91 adult patients exposed to JARDIANCE had an eGFR between 45 and 60 mL/min/1.73 m2, and 97 patients exposed to JARDIANCE had an eGFR between 30 and 45 mL/min/1.73 m2

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Instead, our findings suggest genetically predicted l-carnitine could be linked to higher risk of CAD overall and in men, and heart failure overall

Male, 18-week-old C57BL/6J mice, maintained on a 60% high-fat diet (HFD