Effects of dapagliflozin compared with sitagliptin and metformin in drug-nave Japanese patients with type 2 diabetes: A 12-week, open-label, randomized, active-controlled trial
These observations seem to confirm not only the metabolic but also the immunoregulatory effects of these new antidiabetic agents
Lastly, optimum levels of purine metabolites have been associated with the dynamics of clinical symptoms and therapeutic improvements, which may lead to discovery of novel targets for drug development
The FDA-approved formulations for weight loss are semaglutide (Wegovy), liraglutide (Saxenda), and tirzepatide (Zepbound)
N.XiongQ.MillerG.PettegrewJ
The Bottom Line A GLP-1 weight loss plateau is common, frustrating, and almost always explainable