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Zepbound, on the other hand, is FDA-approved for chronic weight management in adults with obesity or overweight who have at least one weight-related condition, and is available in similar weekly doses

Some research protocols account for this by using comparatively lower dosing ranges in female study cohorts, reflecting a generally increased sensitivity to IGF-1 receptor activation a pattern also documented in broader growth hormone axis research, not unique to IGF-1 LR3 specifically

For some patients, this variability means less stable appetite suppression