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For instance, elevated CHAC1 mRNA levels are associated with increased recurrence risk in these cancers, underscoring its clinical relevance ( Pan-cancer analyses reveal that CHAC1 expression is highly variable, being upregulated in many cancers (e.g., breast, ovarian, lung, bladder carcinomas) and downregulated in others (e.g., certain head/neck, kidney, and brain cancers) (Supplementary Table S1

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Nutr Metab Cardiovasc Dis 2010;20:22435

An analysis of free and bound SA levels in the above mentioned tobacco lines revealed a significant increase evident in TMV-inoculated leaves as compared to controls ( Figure 5 )

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