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Treating comorbidities ME/CFS displays an overlap with several autoimmune or immune-mediated diseases that also have chronic fatigue as a main symptom, such as Hashimotos thyroiditis (530), fibromyalgia (FM) (532, 554557), Mast Cell Activation Disorder (532), sleep apnoea (532), IBS (532), secondary depression or anxiety (532), Ehlers-Danlos syndrome (532), and PoTS (532, 558563)

Lancet 394 , 939951 (2019)

Molecular insights into the potential effects of selective estrogen receptor agonists in Alzheimers and Parkinsons diseases

doi: 10.1038/nrg3182 12 ColladoM

So over time, youll naturally recognize: When youre approaching your last dose When its time to prepare a new pen This removes the guesswork completely

A difference of 1 to 2 units on a standard syringe is unlikely to cause problems