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Thiamine, sometimes referred to as the anti-beriberi factor and neurine, is a key component of carbohydrate metabolism and is soluble in polar solvents such as water but insoluble in organic solvents

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doi:10.1097/00000658-200210000-00012

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Chronic muscle spasms are involuntary, sustained contractions of one or more muscles that recur over weeks or months without a single identifiable acute cause

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