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This positions it as an appealing option for those who have not met their goals with tirzepatide vs retatrutide or who desire a more assertive approach to managing their condition

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Yu L, Yang YX, Gong Z, Wan Q, Du Y, Zhou Q, et al

PMC 4888068

Research shows that GLP-1 agonists like semaglutide activate receptor sites throughout the brain and pancreas, triggering cascades that stabilize leptin signaling, dampen cortisol stress responses, and restore insulin sensitivity in people with metabolic dysfunction

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