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Alcohol-related problems often have downstream effects on mood and anxiety, so we expected the effect to be positive on these as well. However, the magnitude of the association surprised the researchers: Because this is a registry-based study, we cannot determine exactly why or how these medications affect mood symptoms, but the association was quite strong

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At this time point, all subjects were continued on the 0.5 mg dose for an additional 24 weeks

Hydration prevents overproduction

The imputation model included age, sex, follow-up duration, dementia outcome, and mean systolic and diastolic BP