NCCN Guidelines insights: genetic/familial high-risk assessment: colorectal, version 1.2021
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This premise is reinforced by the discovery that different immune cells, including B and T lymphocytes, as well as myeloid-lineage cells such as monocytes, eosinophils, and neutrophils, express GLP-1Rs ( 3.1 Innate and adaptive immune response In rat models of systemic inflammation, a GLP-1 RA, exendin, significantly lowered pro-inflammatory cytokine levels, including IL-1, IL-6, TNF-, and interferon-gamma (IFN-) ( in vitro studies, GLP-1 RAs have demonstrated the capacity of promoting an anti-inflammatory state by influencing immune cell differentiation
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Data availability The dataset generated during and/or analyzed during the current study will be available from the corresponding author (MM) upon reasonable request and once the dataset has been fully exploited by the authors
