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Signaling by hepatocyte growth factor in neurons is induced by pharmacological stimulation of synaptic activity

the ultimate result is a shortage of intracellular cysteine (Fig

This situation could result in death if not treated quickly enough by medical professionals

D.Valverde-PozoJ.SorianoM

In 1970, Orlowski and Meister proposed the -glutamyl cycle, which includes the synthesis, breakdown, export and import of GSH as a key process for amino acid uptake (Orlowski and Meister, 1970)