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Tirzepatide is a biologic drug, a 39-amino-acid peptide with a fatty acid modification that gives it its extended half-life

This peak dose is reached after a 16-week titration period that begins at 0.25 mg and increases in 0.25 mg increments

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Remarkably, GSTP1 also possesses a regulatory function: in form of reduced monomer, it interacts with the C-terminus of c-Jun N-terminal kinase (JNK) and negatively regulates the ability of JNK to phosphorylate the Jun protein