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The face can look older or more drawn, even though the patient is healthier overall

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From TRIUMPH-1: systolic blood pressure fell by 12.3 mmHg at 80 weeks, triglycerides reduced by up to 41.0% , and non-HDL cholesterol fell by up to 24.2%

NRIs clinical trials incorporate meticulous monitoring protocols, dose-optimization strategies, and individualized risk assessments to ensure that participants receive maximal benefit with minimal adverse effects

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70 Patients who proactively follow dietary changes may require greater dose reductions of sulphonylureas or insulin to avoid hypoglycaemia