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These processes contribute to myocardial stiffness, impaired relaxation, and microvascular dysfunction, which exacerbate heart failure symptoms and increase cardiovascular risks [4]
Origin of the Name: "Carnitine" comes from the Latin word carn or carnis, meaning flesh and meat, as it was first isolated from animal tissues, particularly red meat
Biological characteristics of GLP-1RAs Molecular structure and pharmacological properties Due to the suboptimal in vivo stability of the native GLP-1 peptide, GLP-1RAs were engineered with structural modifications that mimic endogenous GLP-1 while achieving a prolonged duration of action [15]
doi: 10.1146/annurev-biochem-050410-100030 65