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Here's why B12 doesn't directly cause weight gain: Water-Soluble Nature : Vitamin B12 is a water-soluble vitamin

The decision to add B12 is made by individual prescribers working with compounding pharmacies, which is why B12 only appears in compounded formulations

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It is considered a strong B12 vitamin because of its high bioavailability, which means the body can easily absorb and utilize it

However, there are some groups of people that may be at a greater risk of vitamin B12 overdose