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- Proof of Concept: This is the first clinical evidence of a therapy leading to increased total lung capacity (TLC) and a reduction in radiological fibrosis markers

Increased Plasma Incretin Concentrations Identifies a Subset of Patients With Persistent Congenital Hyperinsulinism Without KATP Channel Gene Defects

Cardiovasc Diabetol (2016) 15:162

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The authors discuss the importance of the mealtime insulin dose reduction protocol when initiating pramlintide therapy, emphasizing that failure to reduce insulin doses accounts for most hypoglycemic events in clinical trials