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Progressive glutathione depletion across trimesters : First trimester: 36% LOWER than non-pregnant Second trimester: 55% LOWER Third trimester: 87% LOWER This generates more NAPQI at precisely the time when glutathione reserves are least able to neutralize itcreating maximum vulnerability

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Discovery of a long-chain carbamoyl aminocarnitine derivative, a reversible carnitine palmitoyltransferase inhibitor with antiketotic and antidiabetic activity