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Wolverine is the cleaner research tool for isolating angiogenesis-plus-migration mechanisms

bioRxiv Available from 110 SavoiaP.RainaG.CamilloL.FarruggioS.MaryD.VeroneseF.et al (2018)

IV doses of 25-400 mcg/kg for safety studies Important: These are experimental doses used in animal studies and cannot be extrapolated to other species due to significant differences in metabolism, pharmacokinetics, receptor expression, peptide degradation rates, and tissue distribution patterns

While limited evidence supports this, the practice is common

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Reduction of the soluble cyclic GMP vasorelaxing system in the vascular wall of stroke-prone spontaneously hypertensive rats: effect of the alpha1 -receptor blocker doxazosin