In Japan, ALS patients received B12 shots of 25,000-50,000mcg (each shot equal to 25-50 pernicious anemia shots all at once), at first daily and then twice a week
Summary In summary, Vitamin B12 is an essential nutrient that plays a vital role in maintaining energy levels, cognitive function, metabolism, and overall health
The longer session allows for a steady, controlled infusion of larger fluid volumes
(Nature Communications) demonstrated that selective NNMT inhibition in diet-induced obese mice produced significant reductions in fat mass and improvements in insulin sensitivity without caloric restriction
Not all B12 that you eat or take in supplements is absorbed and research indicates that to achieve a sufficient daily dose of B12, you should take at least five to 50 micrograms daily or 1,000 to 2,000 micrograms weekly (Del Bo et al., 2019
That's according to recent tests by ConsumerLab