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Excessive ROS triggers oxidative stress Although ROS production in mitochondria is in balance with an intracellular antioxidant system under physiological conditions, the balance is easy to be disrupted under pathological conditions, such as radiation, hypoxia, cytokines, hyperlipidemia, and hyperglycemia, which results in the accumulation of ROS, facilitating oxidative stress, cell damage, and diseases, such as cancer, cardiovascular disease, neurological disease, respiratory disease, and so on

Fortunately, inactive GSSG can be recycled back into the active GSH form, thanks to the glutathione reductase enzyme

Pay close attention to your body's signals and speak with your doctor about any concerns that you may have

Ophthalmol Glaucoma

Andersson & Arner, 2004)

10.1039/d2fo04063h 8 AllertonT