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What they found: Dose-dependent stimulation of type II collagen (up to 2.5 baseline at 100 nM) Stimulation of aggrecan (up to 1.8 baseline) Inhibition of MMP-13 by ~40 % Partial protection against IL-1-induced matrix degradation Why it matters: It opened a completely new research area for AOD-9604 beyond lipolysis
A review of case studies reported that intravenous administration of 16 mL vitamin C, 5 mL magnesium, 4 mL calcium, 2 mL B6, and 1 mL each of B12, B5, and B complex improved migraine headaches (51)
It is a naturally occurring fragment of the alpha-melanocyte-stimulating hormone (-MSH)
What does all this data say
The 28-day rule why exactly 28 days The 28-day window comes from Pfizer/Hospira prescribing information for bacteriostatic water for injection