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Catalpol alleviates liver injury in T2DM rats through PPAR/NF-B signaling pathway

In scientific literature, senolytic strategies are also explored in models of age-related diseases where senescence is implicated, such as fibrosis, osteoarthritis, metabolic dysfunction, vascular aging, and certain therapy-induced senescence settings

Mol Cell 81(11):2303-2316.e2308 Tran TQ, Lowman XH, Reid MA, Mendez-Dorantes C, Pan M, Yang Y, Kong M (2017) Tumor-associated mutant p53 promotes cancer cell survival upon glutamine deprivation through p21 induction

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Butenolides, such as -butyrolactone, are commonly used as precursors in the synthesis of various chemical compounds