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M., Takahashi N., Miyabe K., et al., Immunoglobulin Light Chain Amyloidosis With Severe Liver Dysfunction Accompanied by Factor X Deficiency, Internal Medicine 58, no

A number of observational studies have demonstrated that systemic sKlotho levels are downregulated in CKD animal models and CKD patients, and it was further reduced as the eGFR declined (Shimamura et al., 2012

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