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doi: 10.1186/s12916-022-02236-0 9 TrasandeLZoellerRTHassUKortenkampAGrandjeanPMyersJPet al

Aerobic activity and resistance training together are consistently linked to measurable visceral fat loss, even before major changes appear on a scale, and combining moderate aerobic exercise with weight or resistance training helps burn calories and tap into stored visceral fat specifically

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People taking placebo lost an average of 6 lbs (or ~2.5% body weight)

First-line use of vepdegestrant in combination with palbociclib is also being evaluated in the Phase 3 VERITAC-3 clinical trial (NCT05909397) in patients with ER-positive, HER2-negative breast cancer who have not received prior systemic anti-cancer treatment for advanced disease

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