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Nevertheless, exenatide was shown to dampen alcohol-related cue reactivity in the ventral striatum, as measured by fMRI, and was associated with lower dopamine transporter levels (Klausen et al., 2022)
Thus, a shift toward increased clinical utility is influencing the industry competition in favor of GLP-1 receptor agonists and attracting investments into research and development projects aimed at improving therapeutic options
[1] Losing muscle alongside fat matters because muscle is metabolically active tissue
Besides protective effects on substance use disorders, the authors analyzed the impact of GLP-1 receptor agonists on body weight management, body mass index (BMI), and glycated hemoglobin level (a measure of glycemic control)
Hyperparathyroidism in MEN2A Hyperparathyroidism is an uncommon manifestation of MEN2A (5% to 10%)