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Instead, we utilised the high nucleophilic reactivity of RSS and RS(S) n S (due to their low pK a and the -effect of the non-terminal sulfur atom) that enables reaction with iodoacetamide (IAM) to generate reaction products that incorporate the terminal sulfane sulfur (Fig

However, euthyroid individuals are usually tolerant to iodine-induced thyroid diseases as their thyroid function rapidly normalizes upon discontinuation of excessive iodine consumption (8, 12)

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