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Thirdly, among interventions that target the microbiome are probiotics, prebiotics, SCFA supplementation, dietary modifications (e.g., Mediterranean diets or those rich in fibers), FMT, and emerging LBPs, all of which combine toward what could be considered a promising frontier in therapeutic potential

Steven Klein, an addiction medicine physician based in Philadelphia with Caron Treatment Centers, agreed to see the participants as private patients, pro bono

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This shift reflects a major change in legal and regulatory risk, driven by federal enforcement priorities, recent proposed legislation, and aggressive intellectual property enforcement by pharmaceutical companies that hold FDA approvals for GLP-1 drugs