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As you might already know tretinoin can increase the turnover of skin cells meaning that it helps shed the older, darker layers of your skin and reveal the newer, lighter ones underneath
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de Jess Garduno-Garcia J, Gastaldelli A, DeFronzo RA, Lertwattanarak R, Holst JJ, Musi N
Funding This work was supported by the Projects of Medicine and Health Science Technology Development Program in Shandong Province [2016WS0499], Shandong Provincial Natural Science Foundation of China Grants [ZR2019PH025]