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That single fractionation study is the proof point researchers still cite more than fifty years later as the origin of the entire copper-peptide research field: a compound identified almost by accident in a liver-aging comparison went on to become one of the most studied metallopeptides in dermal and regenerative research

Zheng K, Dong Y, Yang R, Liang Y, Wu H, He Z (2021) Regulation of ferroptosis by bioactive phytochemicals: implications for medical nutritional therapy

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Additionally, adopting healthy lifestyle practices such as regular exercise, adequate sleep, and stress management can complement the effects of supplementation