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Astragalus polysaccharide alleviates type 2 diabetic rats by reversing the glucose transporters and sweet taste receptors/GLP-1/GLP-1 receptor signaling pathways in the intestine-pancreatic axis

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However, on pre-specified analyses that looked at the occurrence of major cardiovascular events such as death, heart attack, or stroke, those taking retatrutide did not have a statistically significant lower risk of major events than those on placebo

Hypertension 75(6):13341357

Why later

This is important because it may suggest patients with kidney disease have an inherent resistance to these hormones and that medications like Ozempic or Mounjaro that boost the effects of GLP-1 and GIP may be of particular benefit to those who tolerate them, Berglund added