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Under hypoxia or mitochondrial dysfunction, -KG can be converted to citrate by Isocitrate dehydrogenase (IDH 2) catalyzed carboxylation reaction, which is used for the synthesis of amino acids and fatty acids and the production of reducing agent NADPH

People are more familiar with the cosmetic effects of vitamins C and E, but glutathione provides as many benefits as these nutrients and is considered a more powerful antioxidant

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Toxicol Applied Pharmacol 27(2):241-52, 1974) Figure 1

IgE autoantibodies and autoreactive T cells and their role in children and adults with atopic dermatitis