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KIT Pathway Alterations in Mucosal Melanomas of the Vulva and Other Sites

[29] Lazzaroni M, Casini V, Bianchi Porro G

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Research shows that upon activation, AMPK phosphorylates downstream substrates such as acetyl-CoA carboxylase (ACC), which inhibits fatty acid synthesis and promotes fatty acid oxidation, while also suppressing hepatic gluconeogenesis, thereby contributing to the reduction of blood glucose levels (60)

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