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4.1.2 ARF-BP1, PAM and FBXL3 ARF-BP1, also known as HUWE1 in Drosophila , and PAM, also known as highwire in Drosophila , are critical E3 ubiquitin ligases that regulate the stability of REV-ERB, a component of the circadian clock mentioned above that is responsible for repressing genes like BMAL1 (Yin et al., 2010)
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5 Emerging diagnostic biomarkers and predictive tools 5.1 Genetic and transcriptomic biomarkers Genetic and transcriptomic biomarkers, particularly epigenetic regulators, have emerged as critical indicators for predicting endometriosis and associated infertility risks by modulating endometrial receptivity, decidualization, and implantation processes
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